A Combination of anti-epileptic drugs and valacyclovir ameliorated epileptic seizure in pentylenetetrazol-induced kindled mice
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چکیده
منابع مشابه
Ketamine and e.e.g. seizure waves: interaction with anti-epileptic drugs.
When unrestrained cats were with ketamine 2-6 mg kg-1 i.v., anaesthesia was associated with seizure waves induced in the cortical e.e.g. After cats were pretreated with trimethadione 500 mg kg-1 i.p., ketamine did not induce seizure waves. Pretreatment with diphenylhydantoin 25 or 100 mg kg-1 i.p. slightly enhanced seizure waves following ketamine. In both situations the anaesthetic effect of k...
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Using wavelet analysis we have detected the presence of chirps in seizure EEG signals recorded from kindled epileptic rats. Seizures were induced by electrical stimulation of the amygdala and the EEG signals recorded from the amygdala were analyzed using a continuous wavelet transform. A time–frequency representation of the wavelet power spectrum revealed that during seizure the EEG signal is c...
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NEED AND PURPOSE OF REVIEW A number of newer anti-epileptic drugs have been developed in the last few years to improve the treatment outcomes in epilepsy. In this review, we discuss the use of newer anti-epileptic drugs in children. METHODS USED FOR LOCATING, SELECTING, EXTRACTING AND SYNTHESIZING DATA MEDLINE search (1966-2013) was performed using terms newer anti-epileptic drugs, Oxcarbazep...
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Epilepsy represents the most common serious neurological disorder, with a prevalence of 0.4 - 1%. Approximately 30% of patients are resistant to currently available drugs. New anti-epileptic drugs are needed to treat refractory epilepsy, improve upon current therapies, improve the prognosis of epilepsy and to prevent the epileptogenic process. Designing compounds with specific physiological tar...
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The availability of zebrafish larvae model of epileptic seizure provides opportunities to identify novel anticonvulsants for treatment of people with epilepsy. However, the major parameters of zebrafish behavior assay for assessing anti-epileptic drug efficacy existed disparity, which resulted in different results in previous studies. In this study, we chose the high, medium, slow-speed moved d...
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ژورنال
عنوان ژورنال: Proceedings for Annual Meeting of The Japanese Pharmacological Society
سال: 2018
ISSN: 2435-4953
DOI: 10.1254/jpssuppl.wcp2018.0_po3-1-84